Last edited by Mebar
Wednesday, July 29, 2020 | History

4 edition of Immunodeficient animals found in the catalog.

Immunodeficient animals

models for cancer research

  • 263 Want to read
  • 24 Currently reading

Published by Karger in Basel, New York .
Written in English

    Subjects:
  • Tumors -- Transplantation -- Animal models -- Congresses.,
  • Nude mouse -- Congresses.,
  • Tumors -- Immunological aspects -- Animal models -- Congresses.,
  • Cancer -- Animal models -- Congresses.,
  • Neoplasms, Experimental -- immunology -- congresses.,
  • Immunologic Deficiency Syndromes -- congresses.,
  • Disease Models, Animal -- congresses.

  • Edition Notes

    Statementvolume editors, W. Arnold, P. Köpf-Maier, B. Micheel.
    SeriesContributions to oncology = Beiträge zur Onkologie ;, vol. 51, Contributions to oncology ;, vol. 51.
    ContributionsArnold, W. 1939-, Köpf-Maier, P., Micheel, B., Workshop on Immunodeficient Laboratory Animals (1993 : Berlin, Germany)
    Classifications
    LC ClassificationsQR188.6 .I435 1996
    The Physical Object
    Paginationxiii, 229 p. :
    Number of Pages229
    ID Numbers
    Open LibraryOL968142M
    ISBN 103805562705
    LC Control Number96004622

    overview of Charles River’s portfolio of immunodeficient and immunocompetent oncology animal models produced in North America. Selecting the Appropriate Immunodeficient Animal Model Immunodeficient animal models are extremely useful in a wide range of biomedical research, including infectious disease, stem cell, immunology and oncology studies. Movement of animals into a facility for immunodeficient rodents should be held to an absolute minimum unless the facility is dependent on outside supply sources. The single most likely cause of barrier failure is the uncontrolled or ill-advised introduction of new animals into the barrier.

    The classic immunodeficient mutants, nude, scid and rnu, allow unique methods of investigation and provide data of clinical relevance. The present volume presents the state of the art of research work based on the use of these immunodeficient animal models. One section is dedicated to the biological aspects and immunological properties of immunodeficient mutants. 3. Aging and obesity both impair host viral defense. The world is experiencing a major demographic shift toward an older, obese population. By , the world's population aged 60 years and older is expected to total 2 billion, up from million in 2 Aging in and of itself leads to negative changes in innate and adaptive immunity, a process termed immunosenescence. 24 The function of.

    Role of immunodeficient animal models in the development of fructose induced NAFLD ☆ ☆☆ Author links open overlay panel Jashdeep Bhattacharjee a 1 Jerald Mahesh Kumar b 1 Shailendra Arindkar a Barun Das a Upadhyay Pramod a Ramesh C. Juyal a Subeer S. Majumdar a Perumal Nagarajan aCited by: Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit to get more information about this book, to buy it in print, or to download it as a free PDF.


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Immunodeficient animals Download PDF EPUB FB2

The classic immunodeficient mutants nude, scid and rnu have an important function in experimental cancer research: they allow unique methods of investigation and provide data of clinical relevance.

This volume presents the state of the art of research work based on the use of these immunodeficient animal. Immunodeficient Rodents: A Guide To Their Immunobiology, Husbandry, And Use [Institute of Laboratory Animal Resources] on *FREE* shipping on qualifying offers.

Immunodeficient Rodents: A Guide To Their Immunobiology, Husbandry, And UseFormat: Hardcover. ISBN Digitally watermarked, DRM-free Included format: PDF ebooks can be used on all reading devices Immediate eBook download after purchase. Our new e-book, “Best Practices for Care and Husbandry of Immunodeficient Animals” explores ways researchers can ensure optimal health of these unique lab animals.

Providing the best care starts at the commercial breeder level. Immunodeficient Animals for Cancer Research. Editors (view affiliations) Stephen Sparrow; Book.

38 Citations; k Downloads; Log in to check access. Buy eBook. USD Search within book. Front Matter. Pages i-xii. PDF. Immunodeficient animals. Davies. Pages Inherited immunological defects in laboratory animals. Preface In the Institute of Laboratory Animal Resources, National Research Council, convened the Committee on Care and Use of the "Nude" Mouse to prepare guidelines for maintaining, breeding, and rearing mice homozy- gous for the autosomal recessive mutation "nude.".

Antibody Molecule Immunodeficient Animal Haematopoietic Precursor Skin Homograft Rejection Haematopoietic Precursor Cell These keywords were added by machine and not by the authors.

This process is experimental and the keywords may be updated as the learning algorithm improves. This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them.

The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize.

The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a. Buy Immunodeficient Animals: Models for Cancer Research (Contributions to Oncology) by Arnold, W., Kopf-Maier, P., Michael, B.

(ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible : Hardcover. ISBN: OCLC Number: Notes: "Based on the Workshop on Immunodeficient Laboratory Animals held in Berlin in October "--Page xii.

The general conditions outlined in the Guide for the Care and Use of Laboratory Animals (NRC, ) should be used for the maintenance of these animals. Certain immunodeficient rodents [i.e., nude (nu) mice, rats, and hamsters; mice with severe combined immune deficiency (scid); and any multiple mutant strains homozygous for the nu gene] are.

Immunodeficient animal models can be created using either physical, chemical, biological, or surgical methods or by genetic manipulation. The use of immunodeficient animals has been minimal in immunotoxicology research and has been limited, for the most part, to mechanistic studies.

Immunodeficient Animals for Cancer Research | Stephen Sparrow (eds.) | download | B–OK. Download books for free. Find books. Health professionals and those involved in infectious disease research will find Emerging Viruses startling: Harvard researcher Horowitz's studies gather evidence to conclude that AIDS and the Ebola viruses evolved during cancer virus experiments in which monkeys were infected with viral genes from other by: 4.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

New construction materials, shipping containers, and animal-care equipment have helped to protect these animals from disease-producing agents.

Many immunodeficient strains are now commercially available in the pathogen-free state and are maintained under rigid quality-assurance programs to guarantee their microbial and genetic status. Immunodeficient animals: models for cancer research. [W Arnold; P Köpf-Maier; B Micheel;] -- The classic immunodeficient mutants nude, scid and rnu have an important function in experimental cancer research: they allow unique methods of investigation and provide data of clinical relevance.

The efficacy of these systems in protecting immunodeficient animals from infectious agents has not been evaluated. SPECIALIZED HUSBANDRY General Considerations The predominant consideration in the husbandry of immunodeficient ro- dents requiring protection is the very low resistance of these animals to infections of all types.

Cite this entry as: () Immunodeficient Animal. In: Vohr HW. (eds) Encyclopedia of Immunotoxicology. Springer, Berlin. Institute of Laboratory Animal Resources has 18 books on Goodreads with 6 ratings.

Institute of Laboratory Animal Resources’s most popular book is Occupa.Over the past 60 years, numerous studies have provided support for Burnet’s “immune surveillance” hypothesis.

6 Among the simplest observation was that immunodeficient animals and humans had increased incidence of many types of cancers. It is now known that multiple immune cell types contribute to recognizing and destroying transformed by: 1.Immunodeficient animals are those in which the immune system has been impaired to increase susceptibility to infections, tumors, or to similar diseases.

Although immunodeficient animals are considered to be different from hyperresponsive models (that is, animals that develop immunopathies such as diabetes or lupus due to dysregulated immune function), they are often prone to develop .